BDBM50458035 CHEMBL4213219::US10662186, Compound comparative B::US10988476, comparative example B

SMILES CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc3CN(CCc3n2)C(=O)CO)ncc1F

InChI Key InChIKey=HLOKDQHOCMHLLI-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50458035   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-E1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458035(CHEMBL4213219 | US10662186, Compound comparative B...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human CDK4/cyclin D1 using ULight-substrate after 1 hr by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed